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- W2354055742 abstract "Objective: To determine the dissociation constant and partition coefficient of mesylate delavirdine.Methods :The dissociation constant was determined with acid-base titration method in methanol /water solutions with different ratios,the value to infinite diluted in pure water was extrapolated and the partition coefficient was determined with bottle-shaking method by HPLC.Results: The pKa and 1gP of mesylate delavirdine in n-octyl alcohol were 4.635 and 2.907 respectively.Conclusions: mesylate delavirdine is a weak acid with lipophilic property." @default.
- W2354055742 created "2016-06-24" @default.
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- W2354055742 date "2007-01-01" @default.
- W2354055742 modified "2023-09-23" @default.
- W2354055742 title "Determination of the dissociation constant and partition coefficient of mesylate delavirdine" @default.
- W2354055742 hasPublicationYear "2007" @default.
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