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- W2354082941 abstract "AIM:To investigate the correlation between cerebral glucose metabolism and paediatric epilepsy or seizure type and seizure frequency.METHODS:To observe the cerebral glucose metabolism in epileptogenic focus,18F-FDG positron emission computed tomography(PET) brain imaging tests were carried out in 86 cases of paediatric epilepsy diagnosed by EEG and MRI.RESULTS:Compared to control group,significantly statistical differences between children epilepsy group and control group in PET brain imaging were observed(P0.01).The PET brain imaging abnormal rate in epilepsy group was 89.9%(77/86).In abnormal cases,decreased glucose metabolism was shown in 72 cases and increased glucose metabolism was shown in 5 cases.The abnormal PET in different brain districts implicated varieties of epilepsy.Most abnormal brain PET imaging sites in the cases of infantile spasms and Lennox-Gastaut syndrome were observed in bilateral cortex,bilateral brain showed diffuse cortical low metabolic changes,the children with complex partial seizures mainly in temporal lobe.The positive correlations between the abnormal intensity of PET imaging and the severity or seizure frequency were found(P0.01).The more abnormal brain PET imaging was detected,the higher the frequency of attacks or the severer the disease processing was,but no correlation with age(P0.05) was observed.CONCLUSION:Cerebral glucose metabolism of paediatric epilepsy is abnormal.The abnormal PET with varieties of epilepsy is found in different brain district.There is positive correlation between the abnormal intensity of PET imaging and the severity or seizure frequency of epilepsy." @default.
- W2354082941 created "2016-06-24" @default.
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- W2354082941 date "2009-01-01" @default.
- W2354082941 modified "2023-09-23" @default.
- W2354082941 title "Correlation between cerebral glucose metabolism and all sorts of paediatric epilepsy or seizure frequency" @default.
- W2354082941 hasPublicationYear "2009" @default.
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