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- W2354096897 abstract "Objective To study the role of the stomach in exogenous oxalate absorption.Methods The kinetic variation of urinary oxalate excretion (mg/min) in 10 healthy adults and 8 patients with no stomach was investigated before/after an oral spinach oxalate load.The bioavailability of the oxalate load in the healthy adults was calculated and compared with that in the patients.Results The oxalate content in the oral spinach load was 2?567～2?670 mg.The urinary oxalate excretion (mg/min) in the 10 healthy adults was increased significantly 20 min after loading when compared with the basic oxalate excretion level (0.033?1±0.020?3) before loading.The first peak of oxalate excretion appeared at 40 min.The oxalate excretion at 60 min (0.073?2±0.029?4) was double the basic level (P0.01).The second peak appeared at 3rd h.The bioavailability of oxalate 60 min after loading was 50% lower (P0.01) in the patients with no stomach who did not show the “first peak” (0.063±0.062)% than in the healthy adults (0.098±0.071)%.Conclusion The stomach is a powerful oxalate absorption organ under normal physiological conditions.The relationship between stomach dysfunction and urinary calcium oxalate formation needs further investigation." @default.
- W2354096897 created "2016-06-24" @default.
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- W2354096897 date "2003-01-01" @default.
- W2354096897 modified "2023-09-26" @default.
- W2354096897 title "Clinical investigation on gastric oxalate absorption" @default.
- W2354096897 hasPublicationYear "2003" @default.
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