Matches in SemOpenAlex for { <https://semopenalex.org/work/W2354118621> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2354118621 abstract "Objective To investigate the neuroprotective effect of SB239063,the new p38 mitogen-activated protein kinase(MAPK)inhibitor on SHSY5Y neuronal cells against oxygen-glucose deprivation(OGD),and the mechanisms of the neuroprotective effect.Methods SHSY5Y neuroblastoma cells were exposed to OGD with or without SB239063(10μmol/L),cell viability was measured by the MTT assay,activity of p38MAPK was measured by western blot,intracellular concentration of superoxide anion and calcium were evaluated via the fluorescence intensity of HEt and fluo-3/AM.Results Compared with the OGD group,the MTT value was elevated significantly in the SB239063 group(P0.01),the activity of p38MAPK decreased significantly in the SB239063 group(P0.01),the fluorescence intensity of HEt(P0.05)and fluo-3/AM(P0.01)decreased significantly in the SB239063 group.Conclusion SB239063 protects SHSY5Y neuronal cells against OGD by inhibiting p38 MAPK,then reducing the intracellular concentration of superoxide anion and calcium." @default.
- W2354118621 created "2016-06-24" @default.
- W2354118621 creator A5021989628 @default.
- W2354118621 date "2009-01-01" @default.
- W2354118621 modified "2023-09-24" @default.
- W2354118621 title "Role of SB239063,the new p38 mitogen-activated protein kinase inhibitor,on the cell damage of SHSY5Y neuronal cells from oxygen-glucose deprivation" @default.
- W2354118621 hasPublicationYear "2009" @default.
- W2354118621 type Work @default.
- W2354118621 sameAs 2354118621 @default.
- W2354118621 citedByCount "0" @default.
- W2354118621 crossrefType "journal-article" @default.
- W2354118621 hasAuthorship W2354118621A5021989628 @default.
- W2354118621 hasConcept C104317684 @default.
- W2354118621 hasConcept C1491633281 @default.
- W2354118621 hasConcept C153911025 @default.
- W2354118621 hasConcept C181080969 @default.
- W2354118621 hasConcept C181199279 @default.
- W2354118621 hasConcept C184235292 @default.
- W2354118621 hasConcept C185592680 @default.
- W2354118621 hasConcept C25498285 @default.
- W2354118621 hasConcept C2776415932 @default.
- W2354118621 hasConcept C2776715637 @default.
- W2354118621 hasConcept C2779083432 @default.
- W2354118621 hasConcept C2780783641 @default.
- W2354118621 hasConcept C2780795997 @default.
- W2354118621 hasConcept C51551487 @default.
- W2354118621 hasConcept C53227056 @default.
- W2354118621 hasConcept C54355233 @default.
- W2354118621 hasConcept C55493867 @default.
- W2354118621 hasConcept C57074206 @default.
- W2354118621 hasConcept C79879829 @default.
- W2354118621 hasConcept C81885089 @default.
- W2354118621 hasConcept C86803240 @default.
- W2354118621 hasConcept C97029542 @default.
- W2354118621 hasConcept C98274493 @default.
- W2354118621 hasConceptScore W2354118621C104317684 @default.
- W2354118621 hasConceptScore W2354118621C1491633281 @default.
- W2354118621 hasConceptScore W2354118621C153911025 @default.
- W2354118621 hasConceptScore W2354118621C181080969 @default.
- W2354118621 hasConceptScore W2354118621C181199279 @default.
- W2354118621 hasConceptScore W2354118621C184235292 @default.
- W2354118621 hasConceptScore W2354118621C185592680 @default.
- W2354118621 hasConceptScore W2354118621C25498285 @default.
- W2354118621 hasConceptScore W2354118621C2776415932 @default.
- W2354118621 hasConceptScore W2354118621C2776715637 @default.
- W2354118621 hasConceptScore W2354118621C2779083432 @default.
- W2354118621 hasConceptScore W2354118621C2780783641 @default.
- W2354118621 hasConceptScore W2354118621C2780795997 @default.
- W2354118621 hasConceptScore W2354118621C51551487 @default.
- W2354118621 hasConceptScore W2354118621C53227056 @default.
- W2354118621 hasConceptScore W2354118621C54355233 @default.
- W2354118621 hasConceptScore W2354118621C55493867 @default.
- W2354118621 hasConceptScore W2354118621C57074206 @default.
- W2354118621 hasConceptScore W2354118621C79879829 @default.
- W2354118621 hasConceptScore W2354118621C81885089 @default.
- W2354118621 hasConceptScore W2354118621C86803240 @default.
- W2354118621 hasConceptScore W2354118621C97029542 @default.
- W2354118621 hasConceptScore W2354118621C98274493 @default.
- W2354118621 hasLocation W23541186211 @default.
- W2354118621 hasOpenAccess W2354118621 @default.
- W2354118621 hasPrimaryLocation W23541186211 @default.
- W2354118621 hasRelatedWork W2064874184 @default.
- W2354118621 hasRelatedWork W2237489196 @default.
- W2354118621 hasRelatedWork W2352189478 @default.
- W2354118621 hasRelatedWork W2355758512 @default.
- W2354118621 hasRelatedWork W2356777003 @default.
- W2354118621 hasRelatedWork W2364031313 @default.
- W2354118621 hasRelatedWork W2365474659 @default.
- W2354118621 hasRelatedWork W2368722090 @default.
- W2354118621 hasRelatedWork W2368923901 @default.
- W2354118621 hasRelatedWork W2383842912 @default.
- W2354118621 hasRelatedWork W2384722469 @default.
- W2354118621 hasRelatedWork W2386792491 @default.
- W2354118621 hasRelatedWork W2387408316 @default.
- W2354118621 hasRelatedWork W2390667570 @default.
- W2354118621 hasRelatedWork W2394092623 @default.
- W2354118621 hasRelatedWork W2418673068 @default.
- W2354118621 hasRelatedWork W2940715986 @default.
- W2354118621 hasRelatedWork W3029225599 @default.
- W2354118621 hasRelatedWork W3042276809 @default.
- W2354118621 hasRelatedWork W3192286934 @default.
- W2354118621 isParatext "false" @default.
- W2354118621 isRetracted "false" @default.
- W2354118621 magId "2354118621" @default.
- W2354118621 workType "article" @default.