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- W2354157025 abstract "Objective The left ventricular synchrony and systolic function were assessed in patients with coronary artery disease before and after percutaneous coronary intervention(PCI)by real-time three-dimensional echocardiography(RT-3DE).Methods A total of 20 healthy volunteers were performed RT-3DE,and twenty patients with coronary artery disease had RT-3DE before PCI.RT-3DE follow-up was performed 1 week after PCI in all patients with coronary artery disease.Full-volume imaging was recorded before and 1 week after PCI and the data was analyzed by Qlab 6.0 Offline analysis software.A series of global and regional left ventricular volume curves were plotted.The parameters of left ventricular systolic function and regional left ventricular ejection fraction(rLVEF)were calculated.The parameters of left ventricular synchrony:Tmsv-16-sd、Tmsv-12-sd、Tmsv-16-dif、Tmsv-12-dif、Tmsv-16-sd%、Tmsv-12-sd%、Tmsv-16-dif%、Tmsv-12-dif% were obtained by offline analysis software.A paired student's t test was used to compare the dates of coronary artery disease before PCI versus follow-up.Independent-samples t test was used to compare the dates between control group and the group of coronary artery disease.Results All the systolic synchrony parameters Tmsv-16-sd,Tmsv-12-sd,Tmsv-16-dif,Tmsv-12-dif,Tmsv-16-sd%,Tmsv-12-sd%,Tmsv-16-dif% and Tmsv-12-dif% were significant larger in patients with coronary artery disease than those of the control group[(149.2±15.7)ms vs(23.8±20.7)ms,(77.5±63.0)ms vs(15.6±21.3)ms,(308.0±198.8)ms vs(81.9±73.1)ms,(227.2±193.8)ms vs(65.6±90.3)ms,(10.9±6.3)% vs(2.6±2.4)%,(32.9±21.9)% vs(11.2±11.7)%,(24.1±22.1)% vs(6.9±8.6)%,t=-3.714~-6.588,P0.05].After treated with PCI,the Tmsv-16-sd,Tmsv-12-sd,Tmsv-16-dif,Tmsv-12-dif,Tmsv-16-sd% and Tmsv-16-dif% of coronary artery disease patients were lower than those before PCI[(58.8±50.1)ms vs(149.2±15.7)ms,(43.7±54.6)ms vs(77.5±63.0)ms,(192.8±160.8)ms vs(308.0±198.8)ms,(126.9±162.7)ms vs(227.2±193.8)ms,(7.0±6.4)% vs(10.9±6.3)%,(21.7±19.9)% vs(32.9±21.9)%,t=2.597~3.216,P0.05].The rLVEF of anterior regional were lower in the patients with coronary artery disease than those of the control group [basal(46.2±33.6)% vs(65.0±15.0)%,t=-2.147,P0.05 and mid(48.2±17.0)% vs(63.9±20.7)%,t=-2.209,P0.05 and apex(48.7±16.8)% vs(70.3±15.8)%,t=-2.410,P0.05].The rLVEF of anterior regional in the patients with coronary artery disease was improved after PCI compared with before PCI [basal 64.4±14.3)% vs(46.2±33.6)%,t=2.531,P0.05 and mid(59.9±34.2)% vs(48.2±17.0)%,t=2.379,P0.05 and apex(57.0±35.6)% vs(48.7±16.8)%,t=2.418,P0.05].Conclusions RT-3DE can evaluate left ventricular systolic synchrony and regional systolic function.The parameters of left ventricular synchrony and regional systolic function of patients with coronary artery disease are improved after PCI.RT-3DE is useful for evaluating the effects of PCI on left ventricular synchrony and regional systolic function in patients with coronary artery disease." @default.
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- W2354157025 date "2011-01-01" @default.
- W2354157025 modified "2023-09-28" @default.
- W2354157025 title "Assessment of left ventricular systolic synchrony and systolic function by real-time three-dimensional echocardiography in patients with coronary artery disease after percutaneous coronary intervention" @default.
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