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- W2354190033 abstract "Objective:To evaluate the therapeutic effects of leukotriene receptor antagonist(Montelukast) in combination with inhaled corticosteroid (Budesonide)on asthmatic children with allergic rhinitis. Methods:Seventy-four mild to moderate asthmatic children with allergic rhinitis were randomly divided into treating group and control group. Thirty-seven children in control group were treated only with budesonide inhalation(400 μg/d for one month,then reduced to 200 μg/d) for 3 months. On the basis of inhalation, the other thirty-seven children in treating group were added montelukast 5 mg/d orally. Daytime and night asthma symptom scores, allergic rhinitis symptom score and doses of inhaled terbutaline as rescue drug were recorded. Bronchial responsiveness were measured before and after the treatment. Results:After treatment, there was much better improvement in scores of asthma symptoms and allergic rhinitis symptoms and bronchial responsiveness in both groups. Night asthma symptom score , allergic rhinitis symptom score after treatment and average doses of inhaled β2 agonist per week in treating group were significantly lower than those in control group. There was no significant difference in bronchial responsiveness between the two groups.Conclusion:On the basis of low dose inhaled corticosteroid, orally leukotriene receptor antagonist significantly improves the therapeutic efficacy of asthmatic children with allergic rhinitis." @default.
- W2354190033 created "2016-06-24" @default.
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- W2354190033 date "2008-01-01" @default.
- W2354190033 modified "2023-09-26" @default.
- W2354190033 title "Effects of Leukotriene Receptor Antagonist and Inhaled Corticosteroid on Asthmatic Children with Allergic Rhinitis" @default.
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