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- W2354234237 abstract "[Objective] To study the effect of Rhubarb on liver damage and liver regeneration in thioacetamide-induced fulminant hepatic failure(FHF) in rats.[Methods] The rats were randomly divided into normal group,model group,Rhubarb group and lyophilized bovine transfer factor control group. Medicines were given 1 ml/100 g respectively 3 days before hypodermically injected with thioacetamide(TAA) once a day.At the same time,the rats were hypodermically injected with TAA 600 mg·kg~(-1) twice for two days to induce the model of FHF except those in the normal group which were injected with the 0.85 % salt solution hypodermically.Forty-eight hours later,the blood was collected to measure ALT,AST,TB and parameters of liver regeneration such as liver mitotic index and proliferation cell nuclear antigen.[Results] Rhubarb ould obviously decrease ALT,AST,TB and improve liver mitotic index and proliferation cell nuclear antigen of rats with FHF,which has significant difference compared with model group and control group(P0.05 or P0.01).[Conclusion]Rhubarb can prevent the development of FHF and improve liver regeneration." @default.
- W2354234237 created "2016-06-24" @default.
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- W2354234237 date "2006-01-01" @default.
- W2354234237 modified "2023-09-25" @default.
- W2354234237 title "Effect of Rhubarb on liver damage and liver regeneration in thioacetamide-induced fulminant hepatic failure in rats" @default.
- W2354234237 hasPublicationYear "2006" @default.
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