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- W2354246980 abstract "Objective To investigate the effect of high intracranial pressure on the cerebral venous sinus thrombosis in rabbit models.Methods Ninety-five health Japanese big-ear rabbit(Lepus brachyurus) were randomly divided into five groups.Ninety rabbit models were established successfully.Group A,group B,group C and group D were treatment group,in which both the posterior 1/3 superior sagittal sinus and its reflux veins were ligated,with the epidural space balloons of 0.2 ml,0.4 ml,0.6 ml placed in group B,group C and group D,respectively.Group E was sham-operated group.Brain water content,the cerebral venous hemorrhagic infarction and pathological changes were observed at 8 h,24 h,and 48 h after operation.Results The water content and the cerebral venous hemorrhagic infarction in brain tissues after operation were higher in group A,group B,group C and group D than those of group E.With the progressive increase of intracranial pressure,the water content and the range of cerebral venous hemorrhagic infarction were increased.Conclusion Intracranial hypertension can significantly increase the brain water content and the range of cerebral venous hemorrhagic infarction in the model of cerebral venous sinus thrombosis in rabbits.Removal of intracranial hypertension can significantly reduce the brain water content and the range of cerebral venous hemorrhagic infarction in the rabbit models of cerebral venous sinus thrombosis." @default.
- W2354246980 created "2016-06-24" @default.
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- W2354246980 date "2012-01-01" @default.
- W2354246980 modified "2023-09-26" @default.
- W2354246980 title "Effect of high intracranial pressure on the cerebral venous sinus thrombosis in the brain tissues of rabbits" @default.
- W2354246980 hasPublicationYear "2012" @default.
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