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- W2354247244 abstract "Objective: To study the effects of transforming growth factor β1 (TGFβ1) and bone morphogenetic protein2 (BMP2) on the differentiation of odontoblasts in vitro. Methods: Trypsin-isolated dental papillae cells from day 17 mandibular first molar were cultured in semi-solid medium for 6ds. Results: Both TGFβ1 and BMP2 stimulated the matrix secretion by dental papillae cells, TGFβ1 and/or BMP2 combined with heparin, stimulated the functional differentiation of odontoblast-like cells and matrix secretion at the periphery of dental papillae. Conclusions: These results demonstrate that both TGFβ1 and BMP2 stimulate the cytological and functional differentiation of preodontoblasts, and both molecules can act synergistically with each other to strengthen their inductive effects." @default.
- W2354247244 created "2016-06-24" @default.
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- W2354247244 date "2005-01-01" @default.
- W2354247244 modified "2023-09-22" @default.
- W2354247244 title "Transforming Growth Factor β1 (TGFβ1) and Bone Morphogenetic Protein 2 (BMP2) Induce Odontoblast-like Cell Differentiation in vitro." @default.
- W2354247244 hasPublicationYear "2005" @default.
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