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- W2354288273 abstract "Objective To investigate the effect of autologous buccal micro-mucosa graft on the vaginal reconstruction in patients with the congenital absence of vagina. Methods In this study, 12 patients were definitely diagnosed with congenital absence of vagina. Island-shaped buccal mucosa was resected into 16 cm2in size, and then was minced into 0.3mm to 0.5 mm fractions. A cavity was generated between the rectum and urethra with the mean 10 cm in length and 4.2cm in diameter.Subsequently, a stent was implanted into this cavity, and then buccal micro-mucosa graft was transplanted into the top and surroundings of the cavity. The postoperative mold was kept for three months, during which daily tic expansion was necessary to soften scar. Results The operation duration was about 50~80 mins. The donor sites in the mouth healed well within 3 days, without the pain and deformity. All cases were followed up for 4~12 months. The depth of neovagina was 7.5to9.8cm(mean 8.5cm) with the width 3.2 ~4.3cm(mean 3.8cm). The lining was pink-colored and smooth, and characterized as good flexibility. Vaginal folds can be observed via the vaginal orifice,and histopathologically identified as nonkeratinizing squamous stratified mucosa. The perineal area was not disturbed. Importantly, five patients were married and satisfied with their sexual life without pain, of whom only one with vaginal bleeding. The others had no sexual life and were still treated by simulation mold, while no pain and bleeding can occur. Following postoperative 6 months, only one case developed shortened vaginal. Conclusion Autologous buccal micro-mucosa graft is suggested as an easy, minimally invasive and realistic method in the vaginal reconstruction, with rapid recovery and no damage to the oral and genital morphology. However the patients with the vaginal reconstruction were still dependent on the mold support, in addition, long-term follow-up was also needed to further identify its long-term effect." @default.
- W2354288273 created "2016-06-24" @default.
- W2354288273 creator A5033333737 @default.
- W2354288273 date "2014-01-01" @default.
- W2354288273 modified "2023-09-23" @default.
- W2354288273 title "To investigate the effect of vaginal reconstruction with autologous buccal micromucosa graft" @default.
- W2354288273 hasPublicationYear "2014" @default.
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