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- W2354291305 abstract "Objective To develop normal limits for left ventricular ejection fraction (LVEF) measured from gated myocardial perfusion SPECT with ~ 99Tc~m-methoxyisobutylisonitrile(MIBI) and ~ 201Tl. Methods Gated myocardial perfusion SPECT with ~ 99Tc~m-MIBI and ~ 201Tl was performed on 277 patients with a low Bayesian likelihood (10%) of coronary artery disease. The patients were grouped into ~ 99Tc~m-MIBI [normotensive subgroup:n=85; hypertension without left ventricular hypertrophy (LVH) subgroup:n=25] and ~ 201Tl (n=167, normotensive subgroup:n=128; hypertension without LVH subgroup:n=39). The resting LVEF was calculated using an automatic gated myocardial perfusion SPECT processing software. Results The hypertension without LVH subgroup had significantly higher resting LVEF values compared with normotensive subgroup (P0.05) in ~ 99Tc~m-MIBI group and ~ 201Tl group. Sex differences were marked: men had significantly lower mean resting LVEF values than women (P0.01). No significant relationship was seen between resting heart rate or age and resting LVEF values (P0.05). The distributions for resting LVEF values in ~ 99Tc~m-MIBI group and ~ 201Tl group were Gaussian (P0.05). The normal limits were LVEF≥45% in ~ 99Tc~m-MIBI (≥45% in men,≥48% in women) and ≥43% in ~ 201Tl (≥42% in men,≥47% in women). Conclusion These normal limits can be evaluated prospectively for their potential clinical value." @default.
- W2354291305 created "2016-06-24" @default.
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- W2354291305 date "2002-01-01" @default.
- W2354291305 modified "2023-09-25" @default.
- W2354291305 title "Development of normal limits for left ventricular ejection fraction measured from gated myocardial perfusion SPECT with ~ (99)Tc~m-MIBI and ~ (201)Tl" @default.
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