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- W2354385265 abstract "Objective To investigate the relationship between male infertility crowds and Y chromosome microdeletions in ShanDong region.Methods Chromosome Karyotype analysis was detected by Peripheral Blood chromosome G-band detection method.There were 260 cases of patients with smaller Y chromosome.The cases were divided into 4 groups: group A,oligozoospermia(130 cases),group B,azoospermia(130 cases),group C,normal male control group(20 cases) and group D,blank control group,AZF microdeletions genetic were detected in the patients with small Y chromosome by multiplex PCR detection technology.Results There were 260 cases of patients with smaller Y chromosome morphology,which detected 54 cases with Y chromosome AZF microdeletion patients,there was no AZF gene deletion in group C,to compare with group A,B,the gene of AZFa,b,c,total loss rate was lower than that in group A,B,there were significant differences(P 0.05).Conclusion The Y chromosome AZF microdeletions maybe is one of the main causes of azoospermia or oligozoospermia.So diagnosis of Y chromosome AZF microdeletions is of great significance in patients with male infertility." @default.
- W2354385265 created "2016-06-24" @default.
- W2354385265 creator A5007985360 @default.
- W2354385265 date "2013-01-01" @default.
- W2354385265 modified "2023-09-23" @default.
- W2354385265 title "Clinical significance of Y chromosome AZF microdeletion diagnosis in 260 infertility patients in Shandong area" @default.
- W2354385265 hasPublicationYear "2013" @default.
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