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- W2354407321 abstract "Objective To investigate the relationship between serum prealbumin(PA),cholinesterase(ChE),fibrosis markers and pathological injury of hepatic tissue in patients with all kinds of hepatitis.Methods Detection of serum PA,ChE and serum fibrosis markers together with liver biopsy was performed in 292 patients with hepatitis.The relationship between those serum components and the grade of inflammation,fibrosis staging in hepatic tissue was analyzed.Results There was a significant difference of PA,ChE and fibrosis markers between the lower grade and higher grade of inflammation(P 0.01).Serum PA and ChE were gradually decreased but fibrosis markers elevated with the progression of hepatic fibrosis,making a marked difference between fibrosis S0～S3 and S4(P 0.01).The relationship between serum PA,ChE,fibrosis markers and the grade of inflammation,fibrosis staging was highly significant(P 0.01).Conclusions Serum PA,ChE and fibrosis markers can signal the level of liver inflammation activity and the extent of hepatic fibrosis.Combined detection of PA,ChE and fibrosis markers may be a noninvasive diagnostic method for the severity of hepatitis." @default.
- W2354407321 created "2016-06-24" @default.
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- W2354407321 date "2006-01-01" @default.
- W2354407321 modified "2023-09-28" @default.
- W2354407321 title "Relationship between serum prealbumin,cholinesterase and pathological injury of hepatic tissue" @default.
- W2354407321 hasPublicationYear "2006" @default.
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