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• W2354418303 abstract "Objective To study the effect of intraoperative amino acids infusion on the fat metabolism and body temperature in the patients undergoing gastrointestinal surgery under general anesthesia combined with epidural block. Methods Thirty-two patients scheduled for gastrointestinal surgery were randomly assigned to receive either compound amino acid injection(18AA-Ⅱ)(group AA) or lactated Ringer's solution(group LR) at a rate of 4 KJ·kg-1·h-1(2 mL·kg-1·h-1) from the induction of anesthesia to the end of surgery.Nasopharyngeal core temperatures were measured,and serum cholesterol,triglyceride,free fatty acid(FFA) and ketone bodies were analyzed before,during and after the surgery. Results Nasopharyngeal temperature declined during the surgery in both groups,however,the temperatures at 2 hours after the beginning of surgery in AA group were significantly higher than those in LR group(P0.05).Nasopharyngeal temperatures rebounded after the surgery.The temperature at 2 hours after the surgery in AA group [(36.89±0.13) ℃] was significantly higher than that in LR group [(36.10±0.15) ℃](P0.05),which significantly decreased compared with 30 minutes before anesthesia [(37.04±0.15) ℃](P0.05).Compared with 30 minutes before anesthesia,serum cholesterol concentrations significantly decreased from 30 minutes to 2 hours after the surgery in both groups(P0.05),while there was no statistical difference between the two groups(P0.05).Compared with 30 minutes before anesthesia,serum triglyceride concentrations after the induction of anesthesia were significantly higher in both groups(P0.05) and significantly decreased at 2 hours after the surgery in LR group(P0.05),however,it did not change significantly in AA group(P0.05).Serum FFA concentrations at 30 minutes and 2 hours after the beginning of surgery in AA group [(0.52±0.15,0.42±0.09)mmol/L] were significantly lower than those in LR group [(0.81±0.24,0.82±0.22)mmol/L,P0.05].Meanwhile,serum FFA concentration of AA group at 2 hours after the surgery [(1.04±0.28)mmol/L] was significantly higher than that in LR group [(0.82±0.16)mmol/L,P0.05].All the ketone body tests were negative. Conclusions Intraoperative infusion of amino acids can effectively prevent hypothermia during and within 2 hours after the surgery,and inhibit lipid mobilization." @default.
• W2354418303 created "2016-06-24" @default.
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• W2354418303 date "2010-01-01" @default.
• W2354418303 modified "2023-09-22" @default.
• W2354418303 title "Effect of intraoperative amino acids infusion on the metabolism of fat and body temperature in the patients undergoing gastrointestinal surgery" @default.
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