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- W2354438987 abstract "Objective To investigate the improvement of central retinal arterial perfusion with thrombolysis treatment by observing changes of fundus fluorescein angiography(FFA) in patients with central retinal artery occlusion(CRAO) before and after the treatment of selective ophthalmic artery thrombolysis.Methods A total of 24 CRAO patients were performed with selective ophthalmic artery thrombolysis in our department from February 2006 to May 2009.Eyeground situations were observed before and after thrombolysis in patients.FFA image,fluorescence opacification branch-retinal artery visualization time and retinal artery-vein visualization time were recorded and compared before thrombolysis,at 48 hours and 1 month after thrombolysis.Results Fluorescence opacification branch-retinal artery visualization time was(28.87±6.85) seconds before thrombolysis,and were(15.21±4.01) seconds and(15.71±3.43) seconds at 48 hours and 1 month after thrombolysis,which had statistical difference with that before thrombolysis(both P0.001).The average retinal artery-vein visualization time was(40.17±8.55) seconds before thrombolysis,which were(22.25±4.73) seconds and(21.71±3.77) seconds at 48 hours and 1 month after thrombolysis,which had significant difference with that before thrombolysis(both P0.001).At 1 month after thrombolysis,the fundus examination showed that retinal edema was gradually decreased,but optic disc and retinal nerve fiber layer were with various degrees of atrophy.Conclusion Selective intervention thrombolysis for CRAO can effectively and timely recover retinal blood supply,shorten fluorescence opacification branch-retinal artery visualization time and retinal artery-vein visualization time with FFA image.Even blood supply of central retinal artery is recovered quickly,retinal nerve tissues are with various degrees of histomorphological injury." @default.
- W2354438987 created "2016-06-24" @default.
- W2354438987 creator A5003880153 @default.
- W2354438987 date "2010-01-01" @default.
- W2354438987 modified "2023-09-23" @default.
- W2354438987 title "Changes of fundus fluorescein angiography in patients with central retinal artery occlusion before and after treatment of selective ophthalmic artery thrombolysis" @default.
- W2354438987 hasPublicationYear "2010" @default.
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