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- W2354549380 abstract "Objective:To investigate the relationship of one-hour postloade plasma glucose with inflammatory factor in different glucose tolerance.Methods:the subjects were divided into four groups:type 2 diabetes(T2DM),impaired glucose tolerance(IGT),normal glucose tolerance(NGT) with 1 hPG higher than 8.0 mmol/L and normal glucose tolerance with 1 hPG lower than 8.0 mmol/L.Compare the general data and Hs-CRP、TNF-α in each group.Results:(1)TNF-α and Hs-CRP were upgraded from NGT to T2DM.The levels of TNF-α and Hs-CRP in NGT which 1 hPG exceeding 8.0 mmol/L were significantly higher than that in NGT with 1 hPG lower than 8.0 mmol/L(P0.01and P0.05) and similar with IGT(P0.05).(2) 1 hPG were positively correlated with TNF-α、TG、 SBP、 HsCRP,(r=0.405;r=0.388;r=0.310;all P0.01,r=0.183;P0.05)and negatively with HDL-C(r=-0.302;P0.01).The correlation of SBP、HDL-C and TG with 1 hPG were harder than that with 2 hPG.(3) Multiple regression analysis showed that TG、TNF-α and SBP were independent related factors influencing 1 hPG.Conclusion:There were the change of Hs-CRP and TNF-α of inflammatory factors and there maybe the presence of abnormal inflammatory reaction in normal glucose tolerance when 1 hPG exceed 8.0 mmol/L,which is correlated with development of IGT or diabetes and vascular lesion and we can't ignore them when we screen the population inclinable to diabetes." @default.
- W2354549380 created "2016-06-24" @default.
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- W2354549380 date "2011-01-01" @default.
- W2354549380 modified "2023-09-24" @default.
- W2354549380 title "The relation of one-hour postloade plasma glucose with inflammatory factor TNF-α and Hs-CRP in different glucose tolerance" @default.
- W2354549380 hasPublicationYear "2011" @default.
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