Matches in SemOpenAlex for { <https://semopenalex.org/work/W2354567861> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2354567861 abstract "Objective To study the gene mutation in mitochondrial DNA in the patients with mitochondrial encephalomyopathies,and the pathogenic mechanism of mitochondrial encephalomyopathies. Methods We studied the characteristics of clinical features and brain CT in 5 patients with mitochondrial encephalomypathies. We used the method of PCR to amplify DNA extracted from muscle specimens from these patients. Then the DNA fragments were digested with the restriction enzyme BglⅠand ApaⅠ,and electrophoresed through 10%PAGE. Results The clinical characteristics of 5 patients with mitochondrial encephalomyopathies,including 3 patients with MELAS and 2 patients with MERRF,were consistent with the finding of other doctors in studying the disease. And we also looked for A→G transient at position 3243 in 1 of 3 patients with MELAS as well as 8344 in 1 of 2 patients with MERRF. Another patient with MERRF had the point mutations at nucleotide 3243 and 8344.And the 2 familial patients with MELAS had no A→G transient at position nt3243 and 8344. Conclusion There was a correlation between the point mutation at nt3243 and MELAS,or at nt8344 and MERRF. There may be two point mutations at nt3243 and nt8344 in the patient with MERRF. Clinical features are still the main basis to diagnose and classify mitochondrial encephalomypathies." @default.
- W2354567861 created "2016-06-24" @default.
- W2354567861 creator A5082830558 @default.
- W2354567861 date "2001-01-01" @default.
- W2354567861 modified "2023-09-26" @default.
- W2354567861 title "The Study of Gene Mutation Associated With Mitochondrial Encephalomyopathies" @default.
- W2354567861 hasPublicationYear "2001" @default.
- W2354567861 type Work @default.
- W2354567861 sameAs 2354567861 @default.
- W2354567861 citedByCount "0" @default.
- W2354567861 crossrefType "journal-article" @default.
- W2354567861 hasAuthorship W2354567861A5082830558 @default.
- W2354567861 hasConcept C104317684 @default.
- W2354567861 hasConcept C151994961 @default.
- W2354567861 hasConcept C176944494 @default.
- W2354567861 hasConcept C24586158 @default.
- W2354567861 hasConcept C2775833069 @default.
- W2354567861 hasConcept C2776287708 @default.
- W2354567861 hasConcept C2777614518 @default.
- W2354567861 hasConcept C2779799828 @default.
- W2354567861 hasConcept C2910199120 @default.
- W2354567861 hasConcept C501734568 @default.
- W2354567861 hasConcept C54355233 @default.
- W2354567861 hasConcept C86803240 @default.
- W2354567861 hasConceptScore W2354567861C104317684 @default.
- W2354567861 hasConceptScore W2354567861C151994961 @default.
- W2354567861 hasConceptScore W2354567861C176944494 @default.
- W2354567861 hasConceptScore W2354567861C24586158 @default.
- W2354567861 hasConceptScore W2354567861C2775833069 @default.
- W2354567861 hasConceptScore W2354567861C2776287708 @default.
- W2354567861 hasConceptScore W2354567861C2777614518 @default.
- W2354567861 hasConceptScore W2354567861C2779799828 @default.
- W2354567861 hasConceptScore W2354567861C2910199120 @default.
- W2354567861 hasConceptScore W2354567861C501734568 @default.
- W2354567861 hasConceptScore W2354567861C54355233 @default.
- W2354567861 hasConceptScore W2354567861C86803240 @default.
- W2354567861 hasLocation W23545678611 @default.
- W2354567861 hasOpenAccess W2354567861 @default.
- W2354567861 hasPrimaryLocation W23545678611 @default.
- W2354567861 hasRelatedWork W1974538162 @default.
- W2354567861 hasRelatedWork W1976805968 @default.
- W2354567861 hasRelatedWork W1988022598 @default.
- W2354567861 hasRelatedWork W2011973496 @default.
- W2354567861 hasRelatedWork W2016156772 @default.
- W2354567861 hasRelatedWork W2016538007 @default.
- W2354567861 hasRelatedWork W2042501512 @default.
- W2354567861 hasRelatedWork W2045409504 @default.
- W2354567861 hasRelatedWork W2053092410 @default.
- W2354567861 hasRelatedWork W2351276185 @default.
- W2354567861 hasRelatedWork W2366067438 @default.
- W2354567861 hasRelatedWork W2369538509 @default.
- W2354567861 hasRelatedWork W2400138124 @default.
- W2354567861 hasRelatedWork W2406344209 @default.
- W2354567861 hasRelatedWork W2408685350 @default.
- W2354567861 hasRelatedWork W2410298457 @default.
- W2354567861 hasRelatedWork W2414740957 @default.
- W2354567861 hasRelatedWork W2417182348 @default.
- W2354567861 hasRelatedWork W2419523016 @default.
- W2354567861 hasRelatedWork W2432732817 @default.
- W2354567861 isParatext "false" @default.
- W2354567861 isRetracted "false" @default.
- W2354567861 magId "2354567861" @default.
- W2354567861 workType "article" @default.