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- W2354570712 abstract "Objective To assess the efficency of heparin flushing or subcutaneous heparin for prevention on catheter-related infections(CRI),catheter-related thrombosis(CRT),catheter occlusion in oncology patients.Methods Randomized controlled trials(RCTs) were searched and identified from Cochrane library,PubMed,EMBASE,CBM,CNKI and related journals.In accordance with inclusion and exclusion criteria,the quality of the included studies was evaluated by Jadad scale.The data of catheter-related infections,catheter-related thrombosis,catheter occlusion were analyzed by RevMan 5.0.Results 9 randomized controlled trials(1819 patients)were included in this review.Meta analysis showed that there were statistically differences on the incidence of CRT [RR=0.39,95%CI(0.23,0.67)],catheter occlusion [RR=0.40,95%CI(0.31,0.50)],catheter-related bacteremia [RR=0.21,95%CI(0.07,0.60)]between heparin flushing group and normal saline group.There was no difference in the incidence of CRT[RR=0.86,95%CI(0.46,1.58)],catheter occlusion[RR=0.92,95%CI(0.40,2.08)],CRI[RR=0.80,95%CI(0.37,1.77)]between receiving either heparin and placebo injection.Conclusion The current evidences show that heparin flushing is an effective and safe way for preventing catheter-related complications and it does not increased the risk of bleeding.However the number of researchs which included in our study is scant,further high-quality,large scale,double-blind randomized controlled trials are still needed." @default.
- W2354570712 created "2016-06-24" @default.
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- W2354570712 date "2011-01-01" @default.
- W2354570712 modified "2023-09-23" @default.
- W2354570712 title "Prevention of Heparin on CRI and CRT in Oncology Patients:A Systematic Review of the Effectiveness" @default.
- W2354570712 hasPublicationYear "2011" @default.
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