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- W2354604162 abstract "Objective To study the relationship between the perception of pain during parturition and endogenous opioid peptide (EOP) levels, and interactions of EOPs. Methods Concentrations of plasma EOPs (β-endorphin, dorphin A_(1-13), leuenkephalin) at deliery were measured immediately by means of radioimmunoassay in 40 term parturients. Results Dorphin A_(1-13) levels were not correlated significantly with emotional scale(ES)in the first stage of labor (r=-0.08,P=0.26), but correlated significantly with that in the second stage of labor negatively (r=-0.31,P=0.04). Plasma levels of β-endorphin and leuenkephalin were not correlated with ES during either the first or the second stage of labor, respectively. Statistically significant and positive correlation was found between β--endorphin and leuenkephalin (r=0.37,P=0.04). No significant correlations were found for β--endorphin and leuenkephalin as compared with dorphin A_(1-13), respectively (r=0.25,P=0.13;r=0.21,P=0.21). Conclusion The elevated concentrations of dorphin A_(1-13) in maternal plasma would attenuate the perception of pain in the second stage of labor of the parturients. The analgesic effect of β-endorphin can be synergized with leuenkephalin." @default.
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- W2354604162 date "2006-01-01" @default.
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- W2354604162 title "Relationship between endogenous opioid peptides and parturient’s perception of pain during parturition" @default.
- W2354604162 hasPublicationYear "2006" @default.
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