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- W2354637425 abstract "Objective:To investigate the effects of benazepril on coagulative and fibrinolytic system. Method:Forty eight patients with acute coronary syndrome were randomized into control group (n=16) and benazepril group (n=32). The control group received routine treatment, and the benazepril group were treated with routine therapy plus benazepril 10mg per day. Blood samples were drawn at the moment of admission and the 3 rd day after admission, respectively.Activated coagulative time (ACT), tissue type plasminogen activator (t PA) and plasminogen activator inhibitor 1 (PAI 1) were measured. Result:In PTCA group,the levels of serum CK MB at 5,30,120 min after PTCA were significantly higher than that before PTCA and those in two control groups at the same times (P 0.01 ).In contrast,the levels of Mg 2+ at 5,30,120,360 min after PTCA were significantly lower than that before PTCA and those in the negative group at the same times (P 0.05 ).In the positive group,the level of Mg 2+ at 5 min after operation was significantly lower than that before operation and those at the corresponding times in the negative group (P 0.05 and P 0.01 respectively).In addition,there was negative relationship between the level of CK MB and Mg 2+ at 30 min after PTCA (P 0.001 ). Conclusion:Benazepril has no effect on the coagulation, but can increase the activity of t PA and decrease the activity of PAI Ⅰ." @default.
- W2354637425 created "2016-06-24" @default.
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- W2354637425 date "2001-01-01" @default.
- W2354637425 modified "2023-09-25" @default.
- W2354637425 title "The effects of benazepril on coagulative and fibrinolytic system in patients with acute coronary syndrome" @default.
- W2354637425 hasPublicationYear "2001" @default.
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