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- W2354649554 abstract "Objective: To explore the relationship among the circulating levels of the Insulin-like growth factor-1 (IGF-1) and the Insulin-like growth factor binding protein-3 (IGFBP-3) in women with pregnancy-induced hypertension syndrome (PIH) and the occurrence, severity of PIH and the neonatal birth weight.Methods:Radioimmunoassay was used to detect serum levels of IGF-I, IGFBP-3 in thirty-three patients with PIH and thirty-two normal pregnancy women.Results:Serum levels of IGF-1 in women with PIH were significantly lower than the normal pregnant women. There was no significant difference in IGFBP-3 in whole groups, But there was positive correlation between IGF-1 and IGFBP-3. The neonatal birth weight reduced as the PIH severity aggravated and there was a significant difference among each group (F=5.453, P=0.002).Conclusion:IGF-1 may be a key of the pathogenesis abd severity of PIH. There is a positive correlation between IGF-1 and neonatal birth weight." @default.
- W2354649554 created "2016-06-24" @default.
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- W2354649554 date "2003-01-01" @default.
- W2354649554 modified "2023-09-25" @default.
- W2354649554 title "Influence of Insulin-like growth factor in pregnancy-induced hypertension syndrome on the fetal development" @default.
- W2354649554 hasPublicationYear "2003" @default.
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