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- W2354696514 abstract "Objective: To investigate the prevalence of periodontal pathogens in the subgingival plaque of patients with coronary heart disease,and the relationship between the distribution of periodontal pathogens and various degrees of chronic periodontitis(CP).Methods: Subgingival plaque samples were harvested from a total of 44 CP patients with coronary heart disease.The bacteria DNA was obtained from subgingival plaque samples using the chelex-100 method.The extracted DNA [Porphyromonas gingivalis (Pg),Haemophilus actinomycetemcomitans(Ha),Fusobacterium nucleatum(Fn),Prevotella intermedia(Pi),Tannerella forsythensis,(Tf)] was examined using the polymerase chain reaction(PCR) technique by means of specific oligonucleotide primers for periodontal bacteria.Results: In the subgingival plaques samples of 44 patients,19 Pg(43.18%),9 Ha(20.45%),27 Pi(61.36%),38 Fn(86.36%) and 41 Tf(93.18%) were detected.One patient was initial CP,only Fn(100%) were detected.Nine patients were moderate CP,6 Pg(66.67%),2 Ha((22.22%)), 7 Pi(77.78%),9 Fn(100%) and 8 Tf(88.89%) were detected.Thirty-eight patients were severe CP,13 Pg((38.24%)),7 Ha(20.59%),20 Pi(58.82%),28 Fn(82.35%) and 33 Tf(97%) were detected.Conclusion: The result indicated that Tf and Fn may play important roles in the pathogenesis of coronary heart disease and certain subgingival bacteria harvested from patients with coronary heart disease may play important roles in the pathogenesis of periodontal disease." @default.
- W2354696514 created "2016-06-24" @default.
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- W2354696514 date "2008-01-01" @default.
- W2354696514 modified "2023-09-27" @default.
- W2354696514 title "Distribution of Periodontal Pathogens in the Subgingival Plaque of Patients with Coronary Heart Disease" @default.
- W2354696514 hasPublicationYear "2008" @default.
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