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- W2354705036 abstract "To determine the possibility of type collagenase(COL- ), aspartate aminotransferase(AST), elastase in the supernatant(EA-s) in gingival crevicular fluid(GCF) as the diagnostic parameters for early periodontal disease through determining their levels in GCF.GCF was sampled with filter strips by entrance-pocket method from ninety patients. The levels of COL-, AST and EA-s were determined separately by ELISA, Roche automatic biochemistry analyzer and the substrate Meosuc-ala-ala-pro-val-NA.The levels of COL-, AST, EA-s were significantly different among periodontitis, gingivitis and healthy group(P<0.001). The GCF volume, probing depth, attachment loss and sulcus bleeding index were positively related to the levels of enzymes. There were also positive relationships among these three enzymes.COL-, AST, EA-s could be helpful in early diagnosis for periodontal disease." @default.
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- W2354705036 date "2002-12-01" @default.
- W2354705036 modified "2023-10-16" @default.
- W2354705036 title "[The detection and clinical significance of three enzymes in gingival crevicular fluid]." @default.
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