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- W2354740394 abstract "Objective: To investigate the reasons of misdiagnosis and missed diagnosis of kidney injury in multiple myeloma. Methods: Analysis of clinical features and results of laboratory of kidney lesion were carried out in 34 cases of multiple myeloma patients. Results: The incidence of kidney lesion was 52.3% (34/65), the most common kidney lesion was chronic renal failure. There was a significant correlation between the quantity of bone marrow plasmacyte or urine Bence-Jones protein and renal function (P0.01).Anemia, β2-microglobulin or multiple bone lesion were correlated with kidney damage(P0.05). The specificity was lack in the initial symptom. The misdiagnosis rate was 70.6%. Conclusion: Proliferation of bone marrow plasmacyte and the quantity or urine Bence-Jones protein are main causes of kidney lesion in multiple myeloma. For unknown anemia, ostealgia, albuminuria, hyperglobulinemia and fracture, the determination of bence-Jones protein, immunoglobulin and immunoelectrophoresia, the multi-position bone marrow puncture, bone marrow biospy and the osteomyelography should be made in time to avoid missed diagnosis. Combination chemotherapy, and keep normal renal function could improve effect and reduce the mortality of multiple myeloma with kidney lesion." @default.
- W2354740394 created "2016-06-24" @default.
- W2354740394 creator A5054696391 @default.
- W2354740394 date "2007-01-01" @default.
- W2354740394 modified "2023-09-27" @default.
- W2354740394 title "Clinical features and correlate factors of 34 patients with kidney lesion in multiple myeloma" @default.
- W2354740394 hasPublicationYear "2007" @default.
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