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- W2354761943 abstract "Lauroyl acetylglucosamine was synthesized in an organic solvent system with Novozym435 as the catalyst.The factors which influenced the lipase-catalyzed reaction,including organic solvent type,DMF concentration,reaction temperature,reaction time,the volumn ratio of the reaction substrates,and the amount of Novozym435 added,were investigated.Result showed that the optimized solvent system was a mixture of tert-butanol and DMF with a volume ratio of 7∶3.The highest productivity was reached when using the optimized solvents and under the reaction conditions as follows:reaction temperature 60℃,molar ratio of acid to sugar 3∶1,sugar concentration 1mmol/L,reaction time 48h,and the amount of enzyme added 20mg/mL.In addition,the antibacterial activity of the synthesized lauroyl acetylglucosamine was investigated.Results indicated an inhibitory effect of lauroyl acetylglucosamine on Gram positive bacteria,while no inhibition on yeast was observed." @default.
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- W2354761943 date "2008-01-01" @default.
- W2354761943 modified "2023-09-27" @default.
- W2354761943 title "Lipase-catalyzed synthesis of lauroyl acetylglucosamine in organic solvents and its antibacterial activity" @default.
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