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- W2354783921 abstract "In this paper,a label-free immunosensor for carcinoembryonic antigen was developed based on hollow graphene ball /polythionine / gold nanocage. Synthesized hollow graphene ball( HGB) was modified on the surface of glassy carbon electrode( GCE) followed by electropolymerizing thionine on it to adsorb gold nanocage. Carcinoembryonic antibody( anti-CEA) was immobilized on the surface of electrode to construct label-free immunosensor for the determination of carcinoembryonic antigen( CEA). When anti-CEA binds with CEA antigen,the formed immunocomplex obstructed electron transfer,which decrease the electrocatalysis of PTh. The decrease of differential pulse voltammetry( DPV) response of PTh was used to realize label-free detection of carcinoembryonic antigen. Under the optimal experimental conditions,the linear range was 0. 5 ~ 80 ng·mL-1with the detection limit of 0. 17 ng·mL-1, the linear correlation coefficient was 0. 9932. This immunosensor has been used to detect CEA in serum sample,the results were satisfactory." @default.
- W2354783921 created "2016-06-24" @default.
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- W2354783921 date "2014-01-01" @default.
- W2354783921 modified "2023-09-23" @default.
- W2354783921 title "A label-free immunosensor for the determination of carcinoembryonic antigen based on HGB /PTh /AuNCs" @default.
- W2354783921 hasPublicationYear "2014" @default.
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