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- W2354788253 abstract "Objective To investigate the level of plasma 8-iso-prostaglandin F2α and insulin resistance in CHD patients,and their significance in the development of CHD.Methods All 130 CHD patients were divided into the group of stable angina pectoris(SAP group,n=43),group of unstable angina pectoris(UAP group,n=41) and group of acute myocardial infarction(AMI group,n=46).The control group included the patients of non-CHD(n=68).The level of plasma 8-iso-prostaglandin F2α was detected by using enzyme-linked immunosorbent assay(ELISA) and the insulin resistance was calculated according to the formula of(HOMA-IR)=FPG×FINS/22.5.All above indexes and Gensini integrals of diseased coronary vessels were analyzed in CHD patients.Results Compared with the control group,the levels of plasma 8-iso-prostaglandin F2α and HOMA-IR increased significantly in other groups(P0.05),and would rise gradually along with the increase of disease coronary vessels and aggravation of CHD(P0.05).Conclusion Exist in vivo oxidative stress in patients with coronary heart disease and insulin resistance,plasma 8-iso-PGF 2α,HOMA-IR to determine the level of severity of coronary heart disease have a certain significance." @default.
- W2354788253 created "2016-06-24" @default.
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- W2354788253 date "2011-01-01" @default.
- W2354788253 modified "2023-09-24" @default.
- W2354788253 title "Changes and clinical significance of plasma 8-iso-prostaglandin F_(2α) and insulin resistance in CHD patients" @default.
- W2354788253 hasPublicationYear "2011" @default.
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