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- W2354804925 abstract "Nine praziquantel analogues were synthesized and screenedagainst Schistosoma japonicum in vitro.The preliminary results indicated that the2-cyclohexyloxycarbonyl analogue 2_a possessed activity comparable to that ofpraziquantel.It implied the great importance of cyclohexyl group in chair con-formation for the antischistosomal activity.The compound 3_d,considered as a se-coazasteroid——12-benzoyl-14,15-seco-8,12-diazaestra-1,3,5(10)-trien-14-one showedremarkable activity at concentration 100μg/ml." @default.
- W2354804925 created "2016-06-24" @default.
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- W2354804925 date "1991-01-01" @default.
- W2354804925 modified "2023-09-25" @default.
- W2354804925 title "SYNTHESIS AND ANTISCHISTOSOMAL ACTIVITY OF PRAZIQUANTEL ANALOGUES" @default.
- W2354804925 hasPublicationYear "1991" @default.
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