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- W2354829577 abstract "Objective:In order to study the relationship between liver damage degree and HBV DNA content difference of serum and ascite in patients with hepatitis B cirrhosis.Methods: The HBV DNA in serum and ascites of patients was detected by real time PCR technology.The related serum biochemical indicators of liver injury degree was assayed by Olympus AU5400 automatic biochemical analyzer.Results: The HBV DNA content of serum was significantly higher than that of ascite(P0.001) in 49 patients with hepatitis B cirrhosis as a whole,and there was a negative correlation between serum A/G ratio and HBVDNA content of serum or ascite,but the negative correlation of HBV DNA content and A/G ratio of ascites showed more significantly(P0.01).Among these patients,42 patients′ serum HBVDNA content were higher than that of ascite.And in this group the HBVDNA content difference of serum and ascite was negatively correlated with DeRitis ratio(P0.05).However,in the rest 7 patients with severe hepatitis B,the HBVDNA content of serum was significantly lower than that of ascite.Conclusion: The HBVDNA content of serum and ascite could reflect the level of replication and activeness of virus,and they were correlated with the liver injury biochemistry indicator.It was helpful to diagnose the severity level of liver injury by analysis of the HBV DNA in serum and ascite together." @default.
- W2354829577 created "2016-06-24" @default.
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- W2354829577 date "2011-01-01" @default.
- W2354829577 modified "2023-09-24" @default.
- W2354829577 title "The relationship between liver injury degree and HBV DNA content difference of serum and ascite in patients with hepatitis B cirrhosis" @default.
- W2354829577 hasPublicationYear "2011" @default.
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