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- W2354840244 abstract "Objective To investigate the changes in acute organphosphorus pesticides poisoning(AOPP) with intermediated myasthenia syndrome(IMS) patients during sequential invasive-noninvasive mechanical ventilation therapy,and evaluate the effects of this new technique.Methods 25 AOPP patients with IMS were ventilated through an endotracheal tube.When the IMS window occurred,the patients were divided into two groups randomly:traditional group (10 cases)and BiPAP group (15 cases).The parameters of hemodynamics,oxygen dynamics were measured at the PIC-Window during invasive mechanical ventilation,two hours after oxygen therapy,after non-invasive mechanical ventilation,and the reintubation rate was calculated.The traditional group was treated with conventional therapy alone.Results There were no difference in clinical characteristics and gas exchange at entry.The myocardial creatase including CK,CK-MB,AST,LDH were decreased,compared with pretreatment(P0.05).There were no significant differences in respiratory and circulatory parameters after treatment in BiPAP group(P0.05).Compared with the traditional group,the time of invasive mechanical ventilation,total time of ventilatory assistance and hospitalized time in ICU/EICU were decreased markedly(P0.05),and the incidence of ventilator associated pneumonia (VAP)was similar in two groups.Reintubation rate was higher in the traditional group(P0.05).Conclusions The IMS patients can tolerate the transition from invasive mechanical ventilation to noninvasive mechanical ventilation.BiPAP can improve ventilation function,and reduce the reintubation rate in regular mechanical ventilation." @default.
- W2354840244 created "2016-06-24" @default.
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- W2354840244 date "2005-01-01" @default.
- W2354840244 modified "2023-09-24" @default.
- W2354840244 title "Sequential invasive-noninvasive mechanical ventilation in intermediate myasthenia syndrome due to acute organphosphorus pesticides poisoning" @default.
- W2354840244 hasPublicationYear "2005" @default.
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