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- W2354867609 abstract "Objective To investigate whether single nucleotide polymorphisms(SNP) of fibroblast growth receptor 2(FGFR2) are associated with breast cancer risk.Methods In the present study of 280 breast cancer patients and 280 cancer-free controls,we tested three FGFR2 polymorphisms(rs2981582,rs2981578A/G and rs2912778) the method of ASA-PCR.Results Differences were found in the genotypes between the breast neoplasm group and the control group of all loci(P 0.05).Among three loci,except rs2912778(P 0.01) in FGFR2 was related to lymph node metastasis,any difference between wild-type and variant-type in clinical pathological factors were not found(all P 0.05).Conclusion The findings indicate that genetic variants in FGFR2 may contribute to breast cancer occurrence." @default.
- W2354867609 created "2016-06-24" @default.
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- W2354867609 date "2012-01-01" @default.
- W2354867609 modified "2023-09-24" @default.
- W2354867609 title "Relative research of FGFR2 Gene SNPs and breast neoplasm" @default.
- W2354867609 hasPublicationYear "2012" @default.
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