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- W2354875595 abstract "Allergic asthma is characterized by airway hyper-responsiveness and chronic airway mucosal inflammation which arises as a consequence of a defect in immune regulation. Pathogenic mechanisms underlying the development of airway inflammation are very complex and not yet entirely clarified. Regulatory T( Treg) cells play a key role in the maintenance and tolerance of immune regulation. T helper 17( Th17) cells typically promote neutrophilic inflammation,and also play important roles in airway hyperresponsiveness. Recently,research on mechanism of asthma has focused on the imbalance between Treg and Th17 cell phenotype. The purpose of this review is to discuss recent findings of the role of these novel populations in allergic asthma and to highlight the pleiotropic effects of these subsets on the development and regulation of airway inflammation." @default.
- W2354875595 created "2016-06-24" @default.
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- W2354875595 date "2015-01-01" @default.
- W2354875595 modified "2023-09-24" @default.
- W2354875595 title "Treg/Th17 Paradigm in asthmatic airway inflammation" @default.
- W2354875595 hasPublicationYear "2015" @default.
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