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- W2354947777 abstract "Objective To introduce a method for extraction and identification of myelin:a sensitization antigen to experimental autoimmune encephalomyelitis.Methods After discontinuous gradient centrifugation, crude myelin was obtained from bovine spinal cord white matter.By means of removing phosphoglycerides, cholesterol and nucleic acid, purified myelin was obtained, and was identified by calculating its purity, main compositions and relative molecule weight.Additionally, its immunologic activity was observed by inducing EAE in guinea pigs.Results The extracted myelin has chemical characteristics and biological activity, and successfully induced experimental autoimmune encephalomyelitis (EAE).Conclusion The extracted myelin has strong immunologic activity, the advantages of the method being convenient materials, easy to manipulate and suitable to wide application." @default.
- W2354947777 created "2016-06-24" @default.
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- W2354947777 date "2002-01-01" @default.
- W2354947777 modified "2023-09-28" @default.
- W2354947777 title "Extraction and Identification of Myelin: A Sensitization Antigen to Experimental Autoimmune Encephlomyelitis" @default.
- W2354947777 hasPublicationYear "2002" @default.
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