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- W2354990267 abstract "Objective:To investigate symptoms of anxiety,depression and curative effect on two subtypes of gastroesophageal reflux disease(GRED):non-erosive reflux disease(NERD)and reflux esophagitis(RE).Methods:68 patients with GERD were divided into two groups,including 34 in NERD group,34 in RE group,who were given Omeprazole 20 mg twice daily and Cisaprice 10 mg three times daily.The treatment lasted for 8 weeks and relief of major symptoms was evaluated 2,4,6,8 weeks after treatment.according to the hospital anxiety and depressive scale(HAD)before and after treatment.Results:The overall rate of effectiveness 2,4,6,8 weeks after treatment in the RE Group was 52.94%,67.65%,82.35%,94.12% respectively and 20.59%,32.35%,41.18%,50.00% in the NERD group,showing an obvious difference(P0.01).HAD in the two groups before treatment showed an obvious difference(P0.01).HAD in the RE group before and after treatment showed an obvious difference(P0.01).HAD in the NERD group before and after treatment showed no difference(P0.05).Conclusion:There were different pathogenesist in the two subtypes of GERD,but the symptoms of anxiety and depression are more severe in the NERD group than the RE group.They may be important factors influencing the effect of the treatment of NERD." @default.
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- W2354990267 date "2008-01-01" @default.
- W2354990267 modified "2023-09-23" @default.
- W2354990267 title "Analysis of Two Subtypes of Gastroesophageal Reflux Disease Combined with Anxiety,Depression and Observation of Its Curative Effect" @default.
- W2354990267 hasPublicationYear "2008" @default.
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