Matches in SemOpenAlex for { <https://semopenalex.org/work/W2355002530> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2355002530 abstract "Objective To examine whether ischemia preconditioning (IPC) can decrease ischemia reperfusion(I/R) injury in retina and investigate the mechanism. Methods Retinal ischemia was induced in SD rats by increasing the intraocular pressure to 14.63kPa for 60 minutes via cannulation into the anterior chamber. Retinal ischemia for 5 minutes constituted the preconditioning stimulus. Rats first underwent IPC and 60 minutes of ische mia 30 minutes, 24 or 72 hours later or they underwent a 5 minute sham PC and 60 minutes of ischemia 24 hours later. Their electroretinography(ERG), Light microscopy(LM),transmission electron microscopy (EM) and the expression of heat shock protein 70(HSP70) were observed and the content of malandialdehyde(MDA) in rat retinas were measured 24 or 72 hours later after 60 minutes ischemia.Results Ischemia induced histologic damage was completely prevented when IPC was performed 24 or 72 hours (but not 30 minutes) before ischemia. In contrast to the sham PC group, the amplitudes had complete recovery of b waves with preischemia basline amplitudes ( P 0.01),and the content of MDA was significantly decreased ( P 0.01).Conclusion IPC provides protection against retinal I/R injury just during limited period of time." @default.
- W2355002530 created "2016-06-24" @default.
- W2355002530 creator A5085083529 @default.
- W2355002530 date "2001-01-01" @default.
- W2355002530 modified "2023-09-25" @default.
- W2355002530 title "Ischemia preconditioning protects against retinal ischemia reperfusion injury in rats" @default.
- W2355002530 hasPublicationYear "2001" @default.
- W2355002530 type Work @default.
- W2355002530 sameAs 2355002530 @default.
- W2355002530 citedByCount "0" @default.
- W2355002530 crossrefType "journal-article" @default.
- W2355002530 hasAuthorship W2355002530A5085083529 @default.
- W2355002530 hasConcept C103796816 @default.
- W2355002530 hasConcept C118487528 @default.
- W2355002530 hasConcept C126322002 @default.
- W2355002530 hasConcept C169760540 @default.
- W2355002530 hasConcept C2777093970 @default.
- W2355002530 hasConcept C2779113765 @default.
- W2355002530 hasConcept C2779311647 @default.
- W2355002530 hasConcept C2780114680 @default.
- W2355002530 hasConcept C2780827179 @default.
- W2355002530 hasConcept C42219234 @default.
- W2355002530 hasConcept C541997718 @default.
- W2355002530 hasConcept C71924100 @default.
- W2355002530 hasConcept C86803240 @default.
- W2355002530 hasConceptScore W2355002530C103796816 @default.
- W2355002530 hasConceptScore W2355002530C118487528 @default.
- W2355002530 hasConceptScore W2355002530C126322002 @default.
- W2355002530 hasConceptScore W2355002530C169760540 @default.
- W2355002530 hasConceptScore W2355002530C2777093970 @default.
- W2355002530 hasConceptScore W2355002530C2779113765 @default.
- W2355002530 hasConceptScore W2355002530C2779311647 @default.
- W2355002530 hasConceptScore W2355002530C2780114680 @default.
- W2355002530 hasConceptScore W2355002530C2780827179 @default.
- W2355002530 hasConceptScore W2355002530C42219234 @default.
- W2355002530 hasConceptScore W2355002530C541997718 @default.
- W2355002530 hasConceptScore W2355002530C71924100 @default.
- W2355002530 hasConceptScore W2355002530C86803240 @default.
- W2355002530 hasLocation W23550025301 @default.
- W2355002530 hasOpenAccess W2355002530 @default.
- W2355002530 hasPrimaryLocation W23550025301 @default.
- W2355002530 hasRelatedWork W1198207132 @default.
- W2355002530 hasRelatedWork W145508215 @default.
- W2355002530 hasRelatedWork W1554668354 @default.
- W2355002530 hasRelatedWork W1992696099 @default.
- W2355002530 hasRelatedWork W2016182679 @default.
- W2355002530 hasRelatedWork W2022790542 @default.
- W2355002530 hasRelatedWork W2034128356 @default.
- W2355002530 hasRelatedWork W2352966134 @default.
- W2355002530 hasRelatedWork W2355906259 @default.
- W2355002530 hasRelatedWork W2363046794 @default.
- W2355002530 hasRelatedWork W2366816959 @default.
- W2355002530 hasRelatedWork W2367206444 @default.
- W2355002530 hasRelatedWork W2367349744 @default.
- W2355002530 hasRelatedWork W2375136687 @default.
- W2355002530 hasRelatedWork W2377219691 @default.
- W2355002530 hasRelatedWork W2377544191 @default.
- W2355002530 hasRelatedWork W2384798332 @default.
- W2355002530 hasRelatedWork W2393204208 @default.
- W2355002530 hasRelatedWork W2413611152 @default.
- W2355002530 hasRelatedWork W3029571559 @default.
- W2355002530 isParatext "false" @default.
- W2355002530 isRetracted "false" @default.
- W2355002530 magId "2355002530" @default.
- W2355002530 workType "article" @default.