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- W2355025828 abstract "Objective To study the significance of fas antigen and erythropoietin receptor(EPOR)ex- pression on bone marrow(BM)erthroid cells in anemia associated with haematopoietic malignances.Methods fas and EPOR expression were detected by flow cytometry assay on BM erythroid cells in haematopoietic ma- lignances,CD_(71)and GPA were chosen as the marker of BM erythroid cells.Results No significant difference of EPOR expression was observed between anemia associated with haematopoietic malignances and iron defi- ciency anemia [(17.21±16.47)% vs(20.17±13.44)%,P0.05 and(11.41±12.14)% vs(14.49±9.77)%,P 0.05)].However,the expression of EPOR on BM erythroid cells were increased significantly in group of haematopoietic malignances [(21.21±8.14)% vs(6.40±5.72)%,P0.05 and(18.30±7.10)% vs(8.71±6.55)%, P0.05)] and the expression of fas seems to be inversly related to Hemoglobin(Hb)levels(r=0.71,P0.05). Conclusion Over apoptosis of erythroid cells might contribute to anemia associated with haematopoietie ma- lignances,lack of EPOR expression on erythroid cells might not the common pathogenesis of anemia." @default.
- W2355025828 created "2016-06-24" @default.
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- W2355025828 date "2007-01-01" @default.
- W2355025828 modified "2023-09-23" @default.
- W2355025828 title "The study of erythropoietin receptor and fas antigen on bone marrow erythroid cells in anemia asso-ciated with haematopoietic malignances" @default.
- W2355025828 hasPublicationYear "2007" @default.
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