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- W2355037496 abstract "Objective To investigate intratumaral microvascular density(IMVD) and the expression of proliferating cell nuclear antigen(PCNA) in breast carcinoma and their clinicopathologic significance.Method The IMVD and the expression of PCNA in 80 primary breast carcinoma were determined by immunohistochemical SP method.The effect of common pre and post operative clinicopathologic feature,IMVD and PCNA expression on 57 patients overal survival was tested by stepwise logistic regression.Results Both IMVD and PCNA expression were closely correlated with axillary lymph node metastasis and histologic grading.There was a significant positive correlation between IMVD and PCNA expression.The clinical stage,axillary lymph node states,IMVD and PCNA were all independent powerful prognostic factors for these patients.Conclusion These findings suggest that the detections of IMVD and PCNA have considerable practical value in reflecting the proliferative activity of breast carcinoma and evaluating the prognosis." @default.
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- W2355037496 modified "2023-09-26" @default.
- W2355037496 title "The intratumoral microvascular density (IMVD) and the expression of proliferating cell nuclear antigen (PCNA) in breast carcinoma and their clinical pathologic significance" @default.
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