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- W2355041863 abstract "Objective To investigate the fasting,and after oral glucose tolerance test(OGTT),the postprandial levels of glucagon-like peptide-1(GLP-1) and glucose-dependent insulinotropic polypeptide(GIP) in Chinese people with different degrees of glucose tolerance.Methods Based on the results of OGTT,180 subjects were divided into three groups:normal glucose tolerance group(NGT group,n=61),impaired glucose tolerance group(IGT group,n=53) and type-2 diabetes mellitus group(T2DM group,n=66).Fasting venous blood and the venous blood 2 hours after OGTT was sampled to detect GLP-1 and GIP levels.Results The fasting GLP-1 level in the T2DM group was significantly lower than that in the NGT and IGT groups(P0.05).There was no significant difference in fasting GLP-1 level between NGT and IGT groups(P0.05).There was no significant difference in GLP-1 level 2 hours after OGTT among all the three groups(P0.05).GIP level gradually increased in the order of NGT,IGT and T2DM both before and after glucose load,and it was positively correlated with glucose levels just after OGTT and 2 hours after OGTT(r=0.384,0.426;P0.05).Conclusion Different GLP-1 and GIP levels may be one of the reasons for different insulin secretion ability between IGT and T2DM." @default.
- W2355041863 created "2016-06-24" @default.
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- W2355041863 date "2011-01-01" @default.
- W2355041863 modified "2023-09-23" @default.
- W2355041863 title "A Study on the Levels of Glucagon-like Peptide-1 and Glucose-dependent Insulinotropic Polypeptide in People with Different Glucose Tolerance Degrees" @default.
- W2355041863 hasPublicationYear "2011" @default.
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