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- W2355080841 abstract "Objective To study the application range of the diagnos ti c parameters for acute respiratory distress syndrome (ARDS) and multiple organ d ysfunction syndrome (MODS) at high altitude after multiple trauma. Met hods A total of 180 cases with severe multiple trauma complicated by A RDS/MODS were divided into three groups according to their originating altitude: Xining-Yumen group (Xi-Yu group, 31 cases, at altitude of 2 261-2 400 m), La nzhou group (56 cases, at altitude of 1 517 m) and Xi'an group (93 cases, at alt itude of 430 m). The receiver operating characteristic curves (ROC curves) of th ree groups were drafted for a comprehensive evaluation of the results according to the diagnostic criteria of WANG Jin-da et al, Marshall et al and ours in con junction with the acute physiology and chronic health evaluation (APACHE-Ⅱ,Ⅲ) . Results In the Xi'an group, accuracy, sensitivity and spec ificity of criteria of WANG Jin-da et al in predicting the outcome were 0.823, 0.833 and 0.731 respectively and those of Marshall et al 0.815, 0.767 and 0.762, respectively. In the Xi-Yu group, however, accuracy, sensitivit y and specifi city of the same criteria of WANG Jin-da et al were 0.788, 0.800 and 0.650 resp ectively, those of Marshall et al 0.869, 1.000 and 0.616 respect ively and those of ours 0.873 , 0.800 and 0.847 respectively. The accuracy of critria of WANG Jin-da et al was the highest in the plain areas but that of ou rs ranked the highest in the high altitude areas. The optimum cutoff points of P aO 2/FiO 2 were 97.6 mm Hg, 131.5 mm Hg and 198.3 mm Hg respectively and the mortalities of severe trauma in Xi-Yu, Lanzhou and Xi'an groups were 16%, 23% a nd 32% respectively. Conclusions ⑴ The difference of diagn ostic parameters for ARDS between plain and high altitude areas has been confirm ed. However, the diagnostic parameters for MODS vary considerably, which needs m ore investigations to ascertain the exact organ from which the differences origi nate. ⑵ In three groups, the cases of cranial trauma with similar scores of APA CHE-Ⅱ, Ⅲ, the death rates of ARDS/MODS decrease with elevation of altitude, a s reveals that the plain criteria can not reflect the clinical practice at high altitude and that criteria for the highland need improvement." @default.
- W2355080841 created "2016-06-24" @default.
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- W2355080841 date "2004-01-01" @default.
- W2355080841 modified "2023-09-25" @default.
- W2355080841 title "Discrimination of diagnostic parameters for severe multiple trauma complicated by acute respiratory distress syndrome and multiple organ dysfunction syndrome" @default.
- W2355080841 hasPublicationYear "2004" @default.
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