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- W2355092010 abstract "Objective To prepare nimesulide immediate-release pellets containing solid dispersions,and characterize drug dissolution property.Methods Nimesulide solid dispersion,which was prepared by hot melting method using PEG6000 as the carrier,was characterized by differential scanning calorimetry(DSC) and scanning electron microscopy(SEM).Subsequently,nimesulide immediate-released pellets were prepared by extrusion-spheronization technology using the solid dispersion.The dissolution of nimesulide from the pellets was determined with paddle method.Results The nimesulide immediate-released pellets had good quality with high yield.Conclusion Dissolution of nimesulide from immediate-released pellets is increased by incorporating solid dispersions." @default.
- W2355092010 created "2016-06-24" @default.
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- W2355092010 date "2008-01-01" @default.
- W2355092010 modified "2023-09-23" @default.
- W2355092010 title "Preparation and characterization of nimesulide immediate-release pellets containing solid dispersions" @default.
- W2355092010 hasPublicationYear "2008" @default.
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