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- W2355103636 abstract "Objective To evaluate the role of insulin-like growth factor binding protein-2 (IGFBP-2) level in the hepatocellular carcinoma (HCC) and contribution to incidence of HCC and possibility in the diagnostic work-up of patients with HCC.Methods The basal serum level of IGFBP-2/3,AFP,IGF-1,IGF-2 and GH in 54 patients with HCC confirmed histologically was compared with that in patients with hepatic cirrhosis and healthy controls.Results The level of IGFBP-2 in the patients with HCC was higher than in the hepatic cirrhosis group and control group (t=4.63,P0.05;t=3.73,P0.01).Four weeks after the resection of HCC,the level of IGFBP-2 was decreased (t=3.52,P0.05).There was no significant difference in the serum levels of GH,IGF-1/2 and IGFBP-3 between HCC group and control group.In HCC,the serum level of IGFBP-2 and AFP had a positive correlation (r=0.51,P0.05).Conclusion Apart from AFP,IGFBP-2 appears to be a suitable marker of the HCC,which can be applied in the diagnosis of patients with HCC." @default.
- W2355103636 created "2016-06-24" @default.
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- W2355103636 date "2007-01-01" @default.
- W2355103636 modified "2023-09-23" @default.
- W2355103636 title "Relationship between insulin-like growth factor binding protein-2 (IGFBP-2) and hepatocellular carcinoma" @default.
- W2355103636 hasPublicationYear "2007" @default.
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