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- W2355130622 abstract "Objective To compare the clinical efficacy of rebamipide with sucralfate in the treatment of chronic non-atrophic gastritis. Methods A total of 97 cases of chronic non-atrophic gastritis treated in Shashi District People's Hospital of Jingzhou City from Mar. 2011 to Mar. 2013 were divided into observation group of 49 cases and control group of 48 cases according to random-number table method. The observation group was given oral rebamipide,while the control group was treated with sucralfate. After 8 weeks of treatment,the clinical symptoms and gastric mucosal sites( MDA) and prostaglandin E2( PGE2)content of the two groups were compared. Results After treatment the total effective rate of the observation group was 95. 92%,of the control group was 87. 50%,the difference was statistically significant( χ2= 4. 663,P 0. 05); the heartburn,acid reflux / abdominal pain remission rate of the observation group were significantly higher than the control group( P 0. 05). The gastric mucosal inflammation,the inflammation of gastric mucosa pathological integral of both groupswere significantly reduced after treatment,with statistically significant difference from before treatment( P 0. 05); and the observation group integral decrease was significantly better than the control group( P 0. 05); the gastric mucosal MDA content of both groups decreased significantly after treatment,the content of PGE2 increased significantly,the difference was statistically significant compared with before treatment( P 0. 05); the observation group's MDA and PGE2 changes were significantly better than the control group' s( P 0. 05). Conclusion Rebamipide can significantly improve the clinical symptoms of patients with chronic non-atrophic gastritis,thus is worth of clinical promotion." @default.
- W2355130622 created "2016-06-24" @default.
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- W2355130622 date "2014-01-01" @default.
- W2355130622 modified "2023-09-26" @default.
- W2355130622 title "Comparison of the Clinical Effect and Protective Effect of Gastric Mucosa of Rebamipide with Sucralfate in the Treatment of Chronic Non-atrophic Gastritis" @default.
- W2355130622 hasPublicationYear "2014" @default.
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