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- W2355142669 abstract "Objective To investigate the effects of different dosages of daidzein on histomorphometry and bone biomechanics in ovariectomized rats.Methods 72 female SD rats of 3 months were divided into six groups by body weight randomly.One group was sham group,and the other rats in 5 groups were operated to cut out their ovaries.Drenched daidzein was given for 6 months and the rats were killed.To measure geometric parameters,histomorphometry and bone biomechanics of the left femur in different groups of rats were observed.Results The area percent of trabecular,the thickness and the number of trabecular in OVX group were all reduced with percentage of 25.8%,8.09%,12.4%,respectively.The bone biology mechanics performance dropped,the maximum load and flexibility load dropped obviously.Some dosages of daidzein [50mg/(kg·bw)] could antagonize these changes(P0.05).Conclusion Some dosages of daidzein [50?mg/(kg·bw)] can improve the histomorphometry and biomechanics of bone of gelding osteoporosis female rats." @default.
- W2355142669 created "2016-06-24" @default.
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- W2355142669 date "2008-01-01" @default.
- W2355142669 modified "2023-09-24" @default.
- W2355142669 title "Effects of daidzein on histomorphometry and bone biomechanics in rats" @default.
- W2355142669 hasPublicationYear "2008" @default.
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