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- W2355147542 abstract "Objective To evaluate the cytotoxicity of carbon fiber composite dust.Methods The NIH/3T3 cells of mice were taken as the target cell and settled dust of carbon fiber composite from aircraft manufacturing workshop as the experiment material.The viability and proliferation of NIH/3T3 cells were tested by MTT assay.The DNA damage was determined with single cell gel electrophoresis(SCGE)technique.Results After exposure the number of cells reduced;dead cells were found.As the exposure dose increased,viable cells gradually decreased,and the phenomenon of cell with adsorbed poison appeared.After reacted with different concentrations of carbon composite dust(100,200,400,and 800 μg/ml)for a certain time,the viability of NIH/3T3 cells reduced showing a time-dose-response relationship.Carbon fiber composite dust could also break the cell DNA into fragments.In exposed group all the percentages of tailed cells,olive tail moment and extent TM increased,the difference was significant in comparison with those of the control group(P0.05).Conclusions The carbon fiber composite dust has evident cytotoxicity and could damage the DNA." @default.
- W2355147542 created "2016-06-24" @default.
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- W2355147542 date "2012-01-01" @default.
- W2355147542 modified "2023-09-26" @default.
- W2355147542 title "Cytotoxicity of mammalian cells induced by carbon fiber composite dust" @default.
- W2355147542 hasPublicationYear "2012" @default.
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