Matches in SemOpenAlex for { <https://semopenalex.org/work/W2355227988> ?p ?o ?g. }
- W2355227988 endingPage "d1653" @default.
- W2355227988 startingPage "d1653" @default.
- W2355227988 abstract "Cellular scaffolds serve as structural components to which various elements of signal transduction pathways can be associated. The association of components on a scaffold can have several important functions, for example they can: 1) associate upstream regulatory components in a cascade that can increase the speed of response to a stimulus; 2) restrict access of substrates to enzymes associated with the scaffold; 3) permit cross talk between distinct signaling pathways, and; 4) aid in the establishment of cellular polarity. The conversion of the mammalian egg into the zygote requires many rapid alterations during a distinct time frame to mediate the biochemical and structural changes that occur. Cellular scaffolds provide a mechanism that can perform these rapid, highly orchestrated changes. They can permit interaction between distinct calcium-dependent pathways and also can provide a means for the calcium signal, that is initiated by fertilization, to act on calcium-independent pathways. This review considers various lines of evidence suggesting that in the mammalian egg, the meiotic spindle serves as a cellular scaffold that permits coordination among several signaling pathways essential for fertilization and the initiation of early development." @default.
- W2355227988 created "2016-06-24" @default.
- W2355227988 creator A5035073824 @default.
- W2355227988 creator A5064050256 @default.
- W2355227988 date "2002-01-01" @default.
- W2355227988 modified "2023-09-25" @default.
- W2355227988 title "Cellular scaffolds in mammalian eggs" @default.
- W2355227988 cites W133549454 @default.
- W2355227988 cites W1482863768 @default.
- W2355227988 cites W1523015514 @default.
- W2355227988 cites W1718468071 @default.
- W2355227988 cites W1848864628 @default.
- W2355227988 cites W1899552864 @default.
- W2355227988 cites W1928407971 @default.
- W2355227988 cites W1969039586 @default.
- W2355227988 cites W1969522570 @default.
- W2355227988 cites W1973841095 @default.
- W2355227988 cites W1974157845 @default.
- W2355227988 cites W1974494495 @default.
- W2355227988 cites W1975513971 @default.
- W2355227988 cites W1978034329 @default.
- W2355227988 cites W1978710724 @default.
- W2355227988 cites W1979739104 @default.
- W2355227988 cites W1979845151 @default.
- W2355227988 cites W1983158430 @default.
- W2355227988 cites W1983769449 @default.
- W2355227988 cites W1985843936 @default.
- W2355227988 cites W1987196719 @default.
- W2355227988 cites W1988863930 @default.
- W2355227988 cites W1995678810 @default.
- W2355227988 cites W2000576401 @default.
- W2355227988 cites W2002079988 @default.
- W2355227988 cites W2010489503 @default.
- W2355227988 cites W2013684579 @default.
- W2355227988 cites W2015797575 @default.
- W2355227988 cites W2019032966 @default.
- W2355227988 cites W2023426132 @default.
- W2355227988 cites W2024666148 @default.
- W2355227988 cites W2025781389 @default.
- W2355227988 cites W2034948159 @default.
- W2355227988 cites W2037570047 @default.
- W2355227988 cites W2040522552 @default.
- W2355227988 cites W2050066579 @default.
- W2355227988 cites W2053594296 @default.
- W2355227988 cites W2053896630 @default.
- W2355227988 cites W2054734305 @default.
- W2355227988 cites W2060385594 @default.
- W2355227988 cites W2061425302 @default.
- W2355227988 cites W2067486558 @default.
- W2355227988 cites W2067666713 @default.
- W2355227988 cites W2069483149 @default.
- W2355227988 cites W2082049565 @default.
- W2355227988 cites W2083940323 @default.
- W2355227988 cites W2086440778 @default.
- W2355227988 cites W2087250057 @default.
- W2355227988 cites W2094831175 @default.
- W2355227988 cites W2095777195 @default.
- W2355227988 cites W2113651151 @default.
- W2355227988 cites W2115358069 @default.
- W2355227988 cites W2117800241 @default.
- W2355227988 cites W2122960526 @default.
- W2355227988 cites W2124541962 @default.
- W2355227988 cites W2127442070 @default.
- W2355227988 cites W2135723950 @default.
- W2355227988 cites W2142751852 @default.
- W2355227988 cites W2145937070 @default.
- W2355227988 cites W2156113971 @default.
- W2355227988 cites W2158584175 @default.
- W2355227988 cites W2316453747 @default.
- W2355227988 cites W2343043741 @default.
- W2355227988 cites W2467202997 @default.
- W2355227988 cites W987526729 @default.
- W2355227988 doi "https://doi.org/10.2741/baluch" @default.
- W2355227988 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12086913" @default.
- W2355227988 hasPublicationYear "2002" @default.
- W2355227988 type Work @default.
- W2355227988 sameAs 2355227988 @default.
- W2355227988 citedByCount "7" @default.
- W2355227988 countsByYear W23552279882015 @default.
- W2355227988 crossrefType "journal-article" @default.
- W2355227988 hasAuthorship W2355227988A5035073824 @default.
- W2355227988 hasAuthorship W2355227988A5064050256 @default.
- W2355227988 hasBestOaLocation W23552279881 @default.
- W2355227988 hasConcept C120665830 @default.
- W2355227988 hasConcept C121332964 @default.
- W2355227988 hasConcept C169822122 @default.
- W2355227988 hasConcept C185592680 @default.
- W2355227988 hasConcept C201571599 @default.
- W2355227988 hasConcept C41008148 @default.
- W2355227988 hasConcept C53645450 @default.
- W2355227988 hasConcept C62478195 @default.
- W2355227988 hasConcept C77088390 @default.
- W2355227988 hasConcept C86803240 @default.
- W2355227988 hasConcept C89429830 @default.
- W2355227988 hasConcept C95444343 @default.
- W2355227988 hasConceptScore W2355227988C120665830 @default.
- W2355227988 hasConceptScore W2355227988C121332964 @default.
- W2355227988 hasConceptScore W2355227988C169822122 @default.