Matches in SemOpenAlex for { <https://semopenalex.org/work/W2355235708> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2355235708 abstract "Objective To investigate the mechanism of cognitive defect induced by intermittent hypoxia in immature rats.Methods Forty male Sprague-Dawley rats(3～4 week,80～100g) were randomly divided into four groups: 2-week intermittent hypoxia group(2IH),4-week intermittent hypoxia group(4IH),2-week control group(2C) and 4-week control group(4C);and 10 in each group.Intermittent hypoxia model was induced by an intermittent hypoxia cabin and the cabin was flushed with 99.99% nitrogen alternating with 99.50% oxygen.The time of one intermittent hypoxia cycle was 90s.At the end of experiments,the serum levels of 8-Iso-PGF2αwas determined by ELISA.Results The serum levels of 8-ISO-PGF2αin 2C,4C,2IH and 4IH groups were(1877.22±695.10) pg/ml,(1708.09±778.31)pg/ml,(17173.80±3082.34)pg/ml and(27098.44±7030.94)pg/ml,respectively.Compared with those in 2C,4C group,2IH and 4IH group had significantly higher levels of 8-ISO-PGF2α(P0.01,respectively).The ultrastructure of hippocampal neurons in intermittent hypoxia groups showed early apoptosis: the broken nuclear membrane,karyopyknosis and swollen mitochondria vacuoles.Conclusion Chronic intermittent hypoxia leads to oxidative stress,which may be associated with hippocampus damage and recognition degradation in weanling rats." @default.
- W2355235708 created "2016-06-24" @default.
- W2355235708 creator A5072202038 @default.
- W2355235708 date "2007-01-01" @default.
- W2355235708 modified "2023-09-23" @default.
- W2355235708 title "The mechanism of cognitive defect induced by chronic intermittent hypoxia in immature rats" @default.
- W2355235708 hasPublicationYear "2007" @default.
- W2355235708 type Work @default.
- W2355235708 sameAs 2355235708 @default.
- W2355235708 citedByCount "0" @default.
- W2355235708 crossrefType "journal-article" @default.
- W2355235708 hasAuthorship W2355235708A5072202038 @default.
- W2355235708 hasConcept C126322002 @default.
- W2355235708 hasConcept C134018914 @default.
- W2355235708 hasConcept C148762608 @default.
- W2355235708 hasConcept C16685009 @default.
- W2355235708 hasConcept C178790620 @default.
- W2355235708 hasConcept C185592680 @default.
- W2355235708 hasConcept C190283241 @default.
- W2355235708 hasConcept C2776006263 @default.
- W2355235708 hasConcept C2776151105 @default.
- W2355235708 hasConcept C2778433245 @default.
- W2355235708 hasConcept C2780796939 @default.
- W2355235708 hasConcept C540031477 @default.
- W2355235708 hasConcept C55493867 @default.
- W2355235708 hasConcept C71924100 @default.
- W2355235708 hasConcept C7836513 @default.
- W2355235708 hasConceptScore W2355235708C126322002 @default.
- W2355235708 hasConceptScore W2355235708C134018914 @default.
- W2355235708 hasConceptScore W2355235708C148762608 @default.
- W2355235708 hasConceptScore W2355235708C16685009 @default.
- W2355235708 hasConceptScore W2355235708C178790620 @default.
- W2355235708 hasConceptScore W2355235708C185592680 @default.
- W2355235708 hasConceptScore W2355235708C190283241 @default.
- W2355235708 hasConceptScore W2355235708C2776006263 @default.
- W2355235708 hasConceptScore W2355235708C2776151105 @default.
- W2355235708 hasConceptScore W2355235708C2778433245 @default.
- W2355235708 hasConceptScore W2355235708C2780796939 @default.
- W2355235708 hasConceptScore W2355235708C540031477 @default.
- W2355235708 hasConceptScore W2355235708C55493867 @default.
- W2355235708 hasConceptScore W2355235708C71924100 @default.
- W2355235708 hasConceptScore W2355235708C7836513 @default.
- W2355235708 hasLocation W23552357081 @default.
- W2355235708 hasOpenAccess W2355235708 @default.
- W2355235708 hasPrimaryLocation W23552357081 @default.
- W2355235708 hasRelatedWork W1969632161 @default.
- W2355235708 hasRelatedWork W1988242244 @default.
- W2355235708 hasRelatedWork W2038688666 @default.
- W2355235708 hasRelatedWork W2054639370 @default.
- W2355235708 hasRelatedWork W2056754767 @default.
- W2355235708 hasRelatedWork W2073297883 @default.
- W2355235708 hasRelatedWork W2081123068 @default.
- W2355235708 hasRelatedWork W2149535563 @default.
- W2355235708 hasRelatedWork W2348209759 @default.
- W2355235708 hasRelatedWork W2349757721 @default.
- W2355235708 hasRelatedWork W2353984217 @default.
- W2355235708 hasRelatedWork W2364940284 @default.
- W2355235708 hasRelatedWork W2369462413 @default.
- W2355235708 hasRelatedWork W2376335896 @default.
- W2355235708 hasRelatedWork W2381522603 @default.
- W2355235708 hasRelatedWork W2390876687 @default.
- W2355235708 hasRelatedWork W2917828088 @default.
- W2355235708 hasRelatedWork W3030323697 @default.
- W2355235708 hasRelatedWork W3032861950 @default.
- W2355235708 hasRelatedWork W2339529259 @default.
- W2355235708 isParatext "false" @default.
- W2355235708 isRetracted "false" @default.
- W2355235708 magId "2355235708" @default.
- W2355235708 workType "article" @default.