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- W2355237636 abstract "Objective To detect the expression of visfatin in visceral adipose and serum level of visfatin in rats with diabetic mellitus(DM),and to explore the effects of visfatin on the correlated factors of diabetic mellitus.Methods The expression of visfatin mRNA in visceral adiopose and serum level of visfatin in rats with DM were examined.The relationships between visfatin and fasting blood glucose(FBG),fasting insulin(Fins),free fat acid(FFA),triglyceride(TG),total cholesterol(TC),homeostasis model assessment-insulin resistance index(HOMA-IR),or insulin sensitivity index(ISI) were observed.Results The expression of visfatin mRNA in visceral adipose and the serum level of visfatin were significantly increased in DM rats than those in normal control rats(P0.05).The levels of serum FFA,TG,Fins,and HOMA-IR were significantly increased,whilst ISI were decreased significantly in DM rats than those in normal control rats(all P0.05).Serum level of visfatin was positively correlated with FBG,FFA,and HOMA-IR(P0.05),and was negatively correlated with ISI(P 0.05).Conclusion The expression of visfatin mRNA in visceral adipose and the serum level of visfatin are significantly increased in DM rats.The increasing of visfatin may be related to the metabolism disorder of glycolipids and insulin resistance." @default.
- W2355237636 created "2016-06-24" @default.
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- W2355237636 date "2011-01-01" @default.
- W2355237636 modified "2023-09-23" @default.
- W2355237636 title "Expression of visfatin mRNA in visceral adipose of rats with diabetic mellitus" @default.
- W2355237636 hasPublicationYear "2011" @default.
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