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- W2355241314 abstract "Objective:To observe the prevention of mucositis of Irinotecan induced delayed diarrhea in mice.Methods:Twenty healthy Kunming mice were randomized into 4 groups:control group,Irinotecan group,Octreotidegroup and Irinotecan and Octreotide group.We observe the occurrence of delayed diarrhea,sacrifice the mice on day8,collect small intestines and colons and evaluate the mucositis according to Chiu criteria under light microscope.Results:Compared with mice in Irinotecan group,mice in Octreotide and Irinotecan group had less incidence of delayed diarrhea and alleviated intestinal mucositis.(P 0.05).Conclusion:To some extent,Octreotide could prevent Irinotecan induced delayed diarrhea and alleviate intestine and colon mucositis." @default.
- W2355241314 created "2016-06-24" @default.
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- W2355241314 date "2010-01-01" @default.
- W2355241314 modified "2023-09-23" @default.
- W2355241314 title "Preliminary study of prevention of Octreotide on Irinotecan induced delayed diarrhea intestinal mucositis in mice" @default.
- W2355241314 hasPublicationYear "2010" @default.
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