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- W2355282004 abstract "Objective To observe the changes of liver and kidney function after the blood transfusion that have different doses of free hemoglobin(FHb)simultaneously for the recovery of hemorrhagic shock pigs,so as to provide guidance of banked blood with high concentration of FHb during war injury through understanding FHb impact on the animals.Method Different doses of FHb were given in transvenous approach in the recovery of shock,and vital signs and the function of liver and kidney during 48 hours were monitored.Then the incidence of multiple organ dysfunction syndrome(MODS)is calculated.Result There was statistical difference of liver and kidney function after FHb10mg/kg infusion in pigs compared to control group.There was significantly difference of liver and kidney function after FHb15mg/kg infusion compared to the control group.The incidence of MODS increased significantly.Conclusion The high dose(more than 10 mg/Kg)of FHb influences greatly on the liver and kidney function in hemorrhagic shock,and increases the incidence of MODS.The tolerance dose of the pigs for free hemoglobin is about 10 mg/kg or so.The infusion of less than 10 mg/kg for pigs in hemorrhagic shock is relatively safe." @default.
- W2355282004 created "2016-06-24" @default.
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- W2355282004 date "2009-01-01" @default.
- W2355282004 modified "2023-09-25" @default.
- W2355282004 title "The changes of liver and kidney function after the infusion of different dose of free hemoglobin in hemorrhagic shock pigs" @default.
- W2355282004 hasPublicationYear "2009" @default.
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