FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2355282938> ?p ?o ?g. }

• W2355282938 endingPage "144" @default.
• W2355282938 startingPage "144" @default.
• W2355282938 abstract "The dermaseptin antimicrobial peptide family contains members of 27–34 amino acids in length that have been predominantly isolated from the skins/skin secretions of phyllomedusine leaf frogs. By use of a degenerate primer in Rapid amplification of cDNA ends (RACE) PCR designed to a common conserved domain within the 5′-untranslated regions of previously-characterized dermaseptin encoding cDNAs, two novel members of this peptide family, named dermaseptin-PD-1 and dermaseptin-PD-2, were identified in the skin secretion of the phyllomedusine frog, Pachymedusa dacnicolor. The primary structures of both peptides were predicted from cloned cDNAs, as well as being confirmed by mass spectral analysis of crude skin secretion fractions resulted from reversed-phase high-performance liquid chromatography. Chemically-synthesized replicates of dermaseptin-PD-1 and dermaseptin-PD-2 were investigated for antimicrobial activity using standard model microorganisms (Gram-positive bacteria, Gram-negative bacteria and a yeast) and for cytotoxicity using mammalian red blood cells. The possibility of synergistic effects between the two peptides and their anti-cancer cell proliferation activities were assessed. The peptides exhibited moderate to high inhibition against the growth of the tested microorganisms and cancer cell lines with low haemolytic activity. Synergistic interaction between the two peptides in inhibiting the proliferation of Escherichia coli and human neuronal glioblastoma cell line, U251MG was also manifested." @default.
• W2355282938 created "2016-06-24" @default.
• W2355282938 creator A5008851776 @default.
• W2355282938 creator A5019505600 @default.
• W2355282938 creator A5021807484 @default.
• W2355282938 creator A5026937697 @default.
• W2355282938 creator A5056801628 @default.
• W2355282938 creator A5060444243 @default.
• W2355282938 creator A5063241635 @default.
• W2355282938 creator A5064313538 @default.
• W2355282938 creator A5068842220 @default.
• W2355282938 creator A5086543126 @default.
• W2355282938 creator A5091432366 @default.
• W2355282938 date "2016-05-12" @default.
• W2355282938 modified "2023-10-16" @default.
• W2355282938 title "Two Novel Dermaseptin-Like Antimicrobial Peptides with Anticancer Activities from the Skin Secretion of Pachymedusa dacnicolor" @default.
• W2355282938 cites W1482180296 @default.
• W2355282938 cites W1495117474 @default.
• W2355282938 cites W1603880431 @default.
• W2355282938 cites W1650643230 @default.
• W2355282938 cites W1922109732 @default.
• W2355282938 cites W1983697287 @default.
• W2355282938 cites W1998206952 @default.
• W2355282938 cites W2006519770 @default.
• W2355282938 cites W2010431403 @default.
• W2355282938 cites W2016562927 @default.
• W2355282938 cites W2022196988 @default.
• W2355282938 cites W2022790636 @default.
• W2355282938 cites W2023530712 @default.
• W2355282938 cites W2035137299 @default.
• W2355282938 cites W2036034982 @default.
• W2355282938 cites W2037312364 @default.
• W2355282938 cites W2046704370 @default.
• W2355282938 cites W2050895876 @default.
• W2355282938 cites W2062133476 @default.
• W2355282938 cites W2066754309 @default.
• W2355282938 cites W2070762622 @default.
• W2355282938 cites W2072375986 @default.
• W2355282938 cites W2072933784 @default.
• W2355282938 cites W2073406729 @default.
• W2355282938 cites W2079468421 @default.
• W2355282938 cites W2100621506 @default.
• W2355282938 cites W2103832463 @default.
• W2355282938 cites W2122305718 @default.
• W2355282938 cites W2135193400 @default.
• W2355282938 cites W2163208625 @default.
• W2355282938 cites W2246824184 @default.
• W2355282938 cites W2279926712 @default.
• W2355282938 cites W2401705497 @default.
• W2355282938 doi "https://doi.org/10.3390/toxins8050144" @default.
• W2355282938 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4885059" @default.
• W2355282938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27187467" @default.
• W2355282938 hasPublicationYear "2016" @default.
• W2355282938 type Work @default.
• W2355282938 sameAs 2355282938 @default.
• W2355282938 citedByCount "32" @default.
• W2355282938 countsByYear W23552829382017 @default.
• W2355282938 countsByYear W23552829382018 @default.
• W2355282938 countsByYear W23552829382019 @default.
• W2355282938 countsByYear W23552829382020 @default.
• W2355282938 countsByYear W23552829382021 @default.
• W2355282938 countsByYear W23552829382022 @default.
• W2355282938 countsByYear W23552829382023 @default.
• W2355282938 crossrefType "journal-article" @default.
• W2355282938 hasAuthorship W2355282938A5008851776 @default.
• W2355282938 hasAuthorship W2355282938A5019505600 @default.
• W2355282938 hasAuthorship W2355282938A5021807484 @default.
• W2355282938 hasAuthorship W2355282938A5026937697 @default.
• W2355282938 hasAuthorship W2355282938A5056801628 @default.
• W2355282938 hasAuthorship W2355282938A5060444243 @default.
• W2355282938 hasAuthorship W2355282938A5063241635 @default.
• W2355282938 hasAuthorship W2355282938A5064313538 @default.
• W2355282938 hasAuthorship W2355282938A5068842220 @default.
• W2355282938 hasAuthorship W2355282938A5086543126 @default.
• W2355282938 hasAuthorship W2355282938A5091432366 @default.
• W2355282938 hasBestOaLocation W23552829381 @default.
• W2355282938 hasConcept C104317684 @default.
• W2355282938 hasConcept C153911025 @default.
• W2355282938 hasConcept C178790620 @default.
• W2355282938 hasConcept C185592680 @default.
• W2355282938 hasConcept C2777103240 @default.
• W2355282938 hasConcept C2779281246 @default.
• W2355282938 hasConcept C4937899 @default.
• W2355282938 hasConcept C523546767 @default.
• W2355282938 hasConcept C537181965 @default.
• W2355282938 hasConcept C540938839 @default.
• W2355282938 hasConcept C54355233 @default.
• W2355282938 hasConcept C547475151 @default.
• W2355282938 hasConcept C55493867 @default.
• W2355282938 hasConcept C86803240 @default.
• W2355282938 hasConcept C89423630 @default.
• W2355282938 hasConceptScore W2355282938C104317684 @default.
• W2355282938 hasConceptScore W2355282938C153911025 @default.
• W2355282938 hasConceptScore W2355282938C178790620 @default.
• W2355282938 hasConceptScore W2355282938C185592680 @default.
• W2355282938 hasConceptScore W2355282938C2777103240 @default.
• W2355282938 hasConceptScore W2355282938C2779281246 @default.
• W2355282938 hasConceptScore W2355282938C4937899 @default.

• next